Retracted: Correlation of Sperm Associated Antigen 11 (SPAG11) and its Isoforms with Varicocele in Rats
نویسندگان
چکیده
[This retracts the article on p. 241 in vol. 13.].
منابع مشابه
Correlation of Sperm Associated Antigen 11 (SPAG11) and its Isoforms with Varicocele in Rats.
BACKGROUND We undertook this study to investigate the variation relationship of sperm associated antigen 11 (Spag11) mRNA expression and SPAG11E protein in the epididymis and spermatozoa of experimental left varicocele (ELV) rats. These findings could contribute to the understanding of the role of epididymal proteins in sperm functions and the mechanism of male infertility induced by varicocele...
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BACKGROUND Sperm binding proteins and their C-terminal peptides of the Sperm Associated Antigen 11 (SPAG11) family were found to play an important role in epididymal innate immunity in addition to their role in sperm maturation. However, the expression of Spag11 transcripts in rodents is not well documented. METHODS Computational analysis was employed to identify novel Spag11 isoforms in the ...
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Beta-defensins are small cationic peptides exhibiting broad spectrum antimicrobial properties. In humans, many beta-defensin genes are located within a cluster on chromosome 8p23. The sperm associated antigen 11 (SPAG11) gene is contained in this cluster and is unusual among the human beta-defensins due to its complex genomic structure and mRNA splicing pattern. Here we report the genomic organ...
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Background: Varicoceles are the abnormal tortuosity and dilatation of the veins of the pampiniform plexus that drain the testis. Recently, studies evaluating the role of oxidative stress in male infertility have shown that infertile men with varicocele have elevated levels of sperm and testicular tissue-derived reactive oxygen species (ROS). Therefore current study was designed to evaluate prot...
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Introduction: Perepubertal varicocele can result in hypotrophy of testes, sperm damage and decrease the function of leydig cells in future. pathophysiology of varicocele is unclear. Increased reactive oxygen species (ROS) is a major theory. There are many controversies in treatment of pediatric varicocele. Flaxseed (FS) is the richest source of lignans with antioxidant properties. The aim of...
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